Workshop to Take Aim at Bacteria

November 18 (Friday), 2016 | Lehigh University, Bethlehem, PA


About the workshop

This workshop is to bring people from academia, industry, and governmental and non-governmental organizations to talk about their research and efforts toward developing antibiotics and vaccines with multidisciplinary technical advances.

Funding for the workshop is provided by:

- Office of Research and Graduate Studies -

- Bioengineering Program -

- Department of Biological Sciences -

Register now!






08:00 - 08:20Registration / Breakfast
08:20 - 09:45Wonpil Im (Chair)
o Alan Snyder Opening Remarks (Vice President and Associate Provost for Research and Graduate Studies)
o Robert Stavenger IMI TRANSLOCATION and ENABLE: Collaborative Drug Discovery in Action
o Mathias Winterhalter Permeation Across the Outer Cell Wall
o Ruben Tommasi Improving Our Understanding of Porin Permeability in Gram-negative Bacteria
09:45 - 10:15Break
10:15 - 11:55Bryan Berger (Chair)
o Margaret C. Bash Outer Membrane Protein Antigenic Diversity and Vaccine Development for the Pathogenic Neisseria
o Marcos Pires Bacterial Immunotherapies Based on Surface Remodeling
o Francesca M. Marassi Membrane Protein Mediators of Pathogen-host Interactions
o Richard W. Pastor MD Simulations AMP Piscidin 1 Indicate Instability of Small Pores
11:55 - 13:20Lunch
13:20 - 15:00Marcos Pires (Chair)
o Angela Brown Inhibition of Cholesterol Binding As an Anti-Virulence Strategy
o Anna Konovalova Rcs Envelope Stress Response Detects and Counteracts Cationic Antimicrobial Peptides
o Phillip E. Klebba High-throughput Screening for Inhibitors of TonB-dependent Iron Transport by Gram-negative Bacteria
o Charlie Brooks In Silico High-throughput Chemical Space Exploration for Inhibitor Refinement Using Multi-Site Lambda Dynamics
15:00 - 16:00Break
16:00 - 17:40Angela Brown (Chair)
o Bryan Berger Design and Selection of Broad-spectrum, Polysaccharide Degrading Enzymes for Polymicrobial Biofilm Removal
o Karen Fleming Driving Forces for Sorting and Folding of Outer Membrane Beta Barrels
o Linda Columbus Bacterial-host interactions: Can Our Approach and Understanding Impact Resistance?
o Wonpil Im Modeling and Simulation of Bacterial Outer Membranes and Interactions with Proteins
18:30 - Dinner



Registration deadline

November 1, 2016



Wonpil Im




Governor's Suite
Iacocca Hall
111 Research Drive
Bethlehem, PA 18015
GPS: 40.601490,-75.359985

Directions to Mountaintop Campus